Improvement of Hyperphosphatemia in Patients Undergoing Chronic Hemodialysis Relying on Internet Online Dietary Guidance
Keywords:
Hemodialysis, Hyperphosphatemia, Serum phosphorus, Internet, Dietary guidance, ComplianceAbstract
Object: To explore the effect of Internet online dietary guidance on improving serum phosphate levels in hemodialysis
patients.Methods: A prospective cohort study enrolled 70 patients undergoing chronic hemodialysis from April 01, 2019 to May 31,
2019. The enrolled patients entered Intellkidney Nutrition WeChat Mini Program and uploaded their photographs of three
meals a day. The nutritionists carried out online assessment and intervention in a timely manner. After the 6-month follow
up period, improvement of hyperphosphatemia had been assessed due to different compliance.Results: The average serum phosphorus level was 2.4±0.6 mmol/L at baseline. After median 6-month follow-up, the prevalence of hyperphosphatemia was 75.8% and the average serum phosphorus level was 2.3±0.7 mmol/L (P=0.017). Compared to the general compliance group, the patients in the good compliance group presented a seemed higher level of serum phosphorus (2.6±0.6 versus 2.3±0.5mmol/L, P=0.055) at baseline but the levels of serum phosphorus and daily average dietary phosphorus intake were significantly reduced during follow-up. Adjusted gender, dietary parameters, serum iPTH and use of phosphorus-reducing drugs during follow-up, the multivariate Logistic analysis indicated that the decreaseof daily average calorie intake (per 1 Kcal/Kg/d, OR 3.003, 95%CI, 1.014-8.897, P=0.047) was independently associated with improvement of hyperphosphatemia. Conclusion: Our preliminary research indicated that effective online dietaryguidance and good compliance to diet control were helpful to decrease the prevalence of hyperphosphatemia in hemodialysis patients.
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