Prevalence and Risk Factors of post-stroke hemiparesis in stroke survivors
DOI:
https://doi.org/10.5281/zenodo.22815091Keywords:
stroke, hemiparesis, motor impairment, prevalence, risk factorsAbstract
Background: Hemiparesis affects up to three-quarters of stroke survivors in the acute period and remains the most common persisting motor impairment after stroke, driving much of the long-term disability burden captured in global stroke registries.
Objective: This review synthesizes published evidence on the prevalence of post-stroke hemiparesis across the acute, subacute, and chronic phases of recovery, and on the demographic, clinical, neuroanatomical, and biochemical factors that predict its occurrence and persistence.
Methods: We synthesized population-based incidence studies, hospital and rehabilitation cohort studies, and systematic reviews addressing motor impairment prevalence, upper- and lower-limb weakness, spasticity, and recovery trajectories after ischemic and hemorrhagic stroke.
Findings: Reported prevalence of any motor weakness at onset ranges from about 50% to 80%, with roughly two-thirds of survivors showing residual upper-limb impairment at six months; age, initial stroke severity, lesion volume and location, diabetes, and delayed rehabilitation onset predict poorer motor outcome and persistent hemiparesis, while early intensive therapy and favorable corticospinal tract integrity favor more complete recovery.
Conclusions: Post-stroke hemiparesis is prevalent, multifactorial, and only partly modifiable once established, underscoring early risk stratification, timely rehabilitation, and continued investment in biomarkers identifying survivors most likely to benefit from intensive motor therapy.
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