A Retrospective Cohort Study of intra-articular corticosteroid injection in elderly patients with joint disease with psoriatic arthritis

Authors

DOI:

https://doi.org/10.5281/zenodo.22814038

Keywords:

psoriatic arthritis, intra-articular corticosteroid, elderly, ultrasound-guided injection, retrospective cohort

Abstract

Graphical abstract

Background: Psoriatic arthritis is harder to manage in later life as joint destruction, comorbid osteoarthritis, and reduced tolerance for systemic immunosuppression converge, leaving intra-articular corticosteroid injection among the few options for a flaring joint.

Objective: This review synthesizes cohort, registry, and trial evidence on intra-articular corticosteroid injection for peripheral joint disease in elderly psoriatic arthritis patients, covering technique, agent choice, safety, and its place alongside systemic therapy.

Methods: We reviewed retrospective cohorts, ultrasound-guided injection trials, registry analyses, and consensus guidance on injection technique, agent selection, safety, and outcome durability in psoriatic and inflammatory arthritis populations.

Findings: Ultrasound guidance improves accuracy and short-term response over palpation, triamcinolone hexacetonide gives longer relief than less crystalline preparations, and elderly patients show a larger glycaemic excursion after injection, compounded by metabolic comorbidity. Osteoarthritis-derived dose ceilings are extrapolated without dedicated psoriatic-arthritis data.

Conclusions: Intra-articular corticosteroid injection remains a valuable adjunct for oligoarticular flares in elderly psoriatic arthritis, used with ultrasound guidance, conservative limits, and glycaemic monitoring alongside systemic therapy.

References

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Graphical abstract

Published

2025-06-23

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Articles