Impact of assisted reproductive technology on Quality of Life in Patients with gestational diabetes

Divya Sharma; A. Iyer; K. Nair

doi:10.5281/zenodo.22813863

Authors

Divya Sharma Department of Clinical Obstetrics and Maternal Health, Tajo Institute for Advanced Gynecology Author https://orcid.org/4268-7027-1908-8882
A. Iyer Department of Clinical Obstetrics and Maternal Health, Godavari Research Center for Gynecology Author https://orcid.org/1888-6574-5943-5651
K. Nair Department of Gynecology, Neva Academy of Obstetrics and Maternal Health Author https://orcid.org/8086-7766-1714-4393

DOI:

https://doi.org/10.5281/zenodo.22813863

Keywords:

assisted reproductive technology, gestational diabetes, quality of life, in vitro fertilization, psychological distress

Abstract

Graphical abstract

Background: Assisted reproductive technology (ART) pregnancies carry a higher risk of gestational diabetes mellitus (GDM) than spontaneously conceived pregnancies, and the combined burden on maternal quality of life (QoL) remains under-studied.

Objective: This review examines the epidemiological link between ART and GDM, the instruments used to assess QoL in this population, and the psychological burden created when a GDM diagnosis is superimposed on an ART pregnancy.

Methods: We synthesized cohort studies, meta-analyses, randomized GDM management trials, and validation studies of quality-of-life and diabetes-distress instruments from the reproductive medicine and obstetric literature.

Findings: ART conception is consistently associated with higher GDM prevalence, generic instruments such as the SF-36 and WHOQOL-BREF remain the default QoL measures used, and ART patients who develop GDM report disproportionately greater psychological distress than either exposure alone would predict.

Conclusions: Routine GDM screening after ART, dedicated quality-of-life instrumentation for this overlapping population, and integrated psychological support alongside lifestyle-first glycemic management offer a realistic path to improving outcomes.

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