Clinical Outcomes of phacoemulsification cataract surgery in Patients with primary open-angle glaucoma

Authors

DOI:

https://doi.org/10.5281/zenodo.22812172

Keywords:

phacoemulsification, cataract surgery, primary open-angle glaucoma, intraocular pressure, micro-invasive glaucoma surgery

Abstract

Graphical abstract

Background: Cataract and primary open-angle glaucoma (POAG) frequently coexist in aging populations, and phacoemulsification is increasingly performed alone or combined with micro-invasive glaucoma surgery (MIGS) in these patients [1].

Objective: This review synthesizes clinical outcomes of phacoemulsification cataract surgery in POAG patients, including intraocular pressure (IOP) change, medication burden, glaucoma progression, and outcomes of combined phaco-MIGS approaches.

Methods: We reviewed randomized trials, prospective and retrospective cohort studies, foundational glaucoma treatment trials, and society guideline documents addressing IOP and medication outcomes after phacoemulsification in open-angle glaucoma.

Findings: Phacoemulsification alone produces a sustained, angle-dependent IOP reduction in POAG eyes that exceeds the effect in nonglaucomatous eyes [9,12], and combining phacoemulsification with a trabecular or Schlemm's canal MIGS device significantly increases the proportion of eyes reaching unmedicated target IOP compared with phacoemulsification alone [21,23].

Conclusions: Surgical planning for POAG patients undergoing cataract surgery should be individualized by baseline pressure, angle configuration, and prior filtration surgery status, with postoperative IOP surveillance remaining essential regardless of technique chosen [33,30].

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Published

2021-08-02

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