fundus photography in the Management of dry eye disease among elderly patients with vision loss
DOI:
https://doi.org/10.5281/zenodo.22812237Keywords:
dry eye disease, fundus photography, meibography, elderly, vision lossAbstract
Background: Dry eye disease prevalence rises with age to roughly 15% in the oldest cohorts, coexisting with the posterior segment diseases driving most irreversible vision loss [1,12].
Objective: To examine dry eye management in elderly patients and how fundus photography and surface imaging support efficient assessment.
Methods: Narrative synthesis of TFOS DEWS II reports, Cochrane reviews, cohorts, and fundus-photography screening literature.
Findings: Meibography documents evaporative dry eye [8], and non-mydriatic fundus photography now screens for retinopathy in the same visit [29,31].
Conclusions: Visual complaints should not be attributed to the ocular surface without a fundus photograph confirming posterior segment health [10,11].
References
Schaumberg, D.A., Sullivan, D.A., Buring, J.E., Dana, M.R. (2003) Prevalence of dry eye syndrome among US women. American Journal of Ophthalmology, 136(2): 318-326. DOI: 10.1016/S0002-9394(03)00218-6
Schaumberg, D.A., Dana, R., Buring, J.E., Sullivan, D.A. (2009) Prevalence of dry eye disease among US men: estimates from the Physicians' Health Studies. Archives of Ophthalmology, 127(6): 763-768. DOI: 10.1001/archophthalmol.2009.103
Moss, S.E., Klein, R., Klein, B.E.K. (2000) Prevalence of and risk factors for dry eye syndrome. Archives of Ophthalmology, 118(9): 1264-1268. DOI: 10.1001/archopht.118.9.1264
Moss, S.E., Klein, R., Klein, B.E.K. (2008) Long-term incidence of dry eye in an older population. Optometry and Vision Science, 85(8): 668-674. DOI: 10.1097/OPX.0b013e318181a947
Craig, J.P., Nichols, K.K., Akpek, E.K., Caffery, B., Dua, H.S., Joo, C.K., et al. (2017) TFOS DEWS II Definition and Classification Report. The Ocular Surface, 15(3): 276-283. DOI: 10.1016/j.jtos.2017.05.008
Stapleton, F., Alves, M., Bunya, V.Y., Jalbert, I., Lekhanont, K., Malet, F., et al. (2017) TFOS DEWS II Epidemiology Report. The Ocular Surface, 15(3): 334-365. DOI: 10.1016/j.jtos.2017.05.003
Bron, A.J., de Paiva, C.S., Chauhan, S.K., Bonini, S., Gabison, E.E., Jain, S., et al. (2017) TFOS DEWS II Pathophysiology Report. The Ocular Surface, 15(3): 438-510. DOI: 10.1016/j.jtos.2017.05.011
Arita, R., Itoh, K., Inoue, K., Amano, S. (2008) Noncontact infrared meibography to document age-related changes of the meibomian glands in a normal population. Ophthalmology, 115(5): 911-915. DOI: 10.1016/j.ophtha.2007.06.031
Nichols, K.K., Foulks, G.N., Bron, A.J., Glasgow, B.J., Dogru, M., Tsubota, K., et al. (2011) The International Workshop on Meibomian Gland Dysfunction: executive summary. Investigative Ophthalmology & Visual Science, 52(4): 1922-1929. DOI: 10.1167/iovs.10-6997a
Congdon, N.G., Friedman, D.S., Lietman, T. (2003) Important causes of visual impairment in the world today. JAMA, 290(15): 2057-2060. DOI: 10.1001/jama.290.15.2057
Wong, W.L., Su, X., Li, X., Cheung, C.M.G., Klein, R., Cheng, C.Y., et al. (2014) Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040. The Lancet Global Health, 2(2): e106-e116. DOI: 10.1016/S2214-109X(13)70145-1
Bourne, R.R.A., Steinmetz, J.D., Saylan, M., Mersha, A.M., Weldemariam, A.T., Wondmeneh, T.G., et al. (2021) Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence projections for 2050. The Lancet Global Health, 9(2): e130-e143. DOI: 10.1016/S2214-109X(20)30425-3
Vehof, J., Kozareva, D., Hysi, P.G., Hammond, C.J. (2014) Prevalence and risk factors of dry eye disease in a British female cohort. British Journal of Ophthalmology, 98(12): 1712-1717. DOI: 10.1136/bjophthalmol-2014-305201
Sullivan, D.A., Rocha, E.M., Aragona, P., Clayton, J.A., Ding, J., Golebiowski, B., et al. (2017) TFOS DEWS II Sex, Gender, and Hormones Report. The Ocular Surface, 15(3): 284-333. DOI: 10.1016/j.jtos.2017.04.001
Miljanovic, B., Dana, R., Sullivan, D.A., Schaumberg, D.A. (2007) Impact of dry eye syndrome on vision-related quality of life. American Journal of Ophthalmology, 143(3): 409-415. DOI: 10.1016/j.ajo.2006.11.060
Yu, J., Asche, C.V., Fairchild, C.J. (2011) The economic burden of dry eye disease in the United States: a decision tree analysis. Cornea, 30(4): 379-387. DOI: 10.1097/ICO.0b013e3181f7f363
Wolffsohn, J.S., Arita, R., Chalmers, R., Djalilian, A., Dogru, M., Dumbleton, K., et al. (2017) TFOS DEWS II Diagnostic Methodology Report. The Ocular Surface, 15(3): 539-574. DOI: 10.1016/j.jtos.2017.05.001
Sullivan, B.D., Whitmer, D., Nichols, K.K., Tomlinson, A., Foulks, G.N., Geerling, G., et al. (2010) An objective approach to dry eye disease severity. Investigative Ophthalmology & Visual Science, 51(12): 6125-6130. DOI: 10.1167/iovs.10-5390
Lemp, M.A., Bron, A.J., Baudouin, C., Benitez Del Castillo, J.M., Geffen, D., Tauber, J., et al. (2011) Tear osmolarity in the diagnosis and management of dry eye disease. American Journal of Ophthalmology, 151(5): 792-798. DOI: 10.1016/j.ajo.2010.10.032
Nichols, K.K., Nichols, J.J., Mitchell, G.L. (2004) The lack of association between signs and symptoms in patients with dry eye disease. Cornea, 23(8): 762-770. DOI: 10.1097/01.ico.0000133997.07144.9e
Schiffman, R.M., Christianson, M.D., Jacobsen, G., Hirsch, J.D., Reis, B.L. (2000) Reliability and validity of the Ocular Surface Disease Index. Archives of Ophthalmology, 118(5): 615-621. DOI: 10.1001/archopht.118.5.615
Baudouin, C., Aragona, P., Van Setten, G., Rolando, M., Irkec, M., Benitez del Castillo, J., et al. (2014) Diagnosing the severity of dry eye: a clear and practical algorithm. British Journal of Ophthalmology, 98(9): 1168-1176. DOI: 10.1136/bjophthalmol-2013-304619
Bron, A.J., Tomlinson, A., Foulks, G.N., Pepose, J.S., Baudouin, C., Geerling, G., et al. (2014) Rethinking dry eye disease: a perspective on clinical implications. The Ocular Surface, 12(2 Suppl): S1-S31. DOI: 10.1016/j.jtos.2014.02.002
Jones, L., Downie, L.E., Korb, D., Benitez-del-Castillo, J.M., Dana, R., Deng, S.X., et al. (2017) TFOS DEWS II Management and Therapy Report. The Ocular Surface, 15(3): 575-628. DOI: 10.1016/j.jtos.2017.05.006
Pucker, A.D., Ng, S.M., Nichols, J.J. (2016) Over the counter (OTC) artificial tear drops for dry eye syndrome. Cochrane Database of Systematic Reviews, 2: CD009729. DOI: 10.1002/14651858.CD009729.pub2
Ervin, A.M., Law, A., Pucker, A.D. (2017) Punctal occlusion for dry eye syndrome. Cochrane Database of Systematic Reviews, 6: CD006775. 10.1002/14651858.CD006775.pub3
Craig, J.P., Chen, Y.H., Turnbull, P.R. (2015) Prospective trial of intense pulsed light for the treatment of meibomian gland dysfunction. Investigative Ophthalmology & Visual Science, 56(3): 1965-1970. DOI: 10.1167/iovs.14-15764
Fraunfelder, F.W., Sciubba, J.J., Mathers, W.D. (2012) The role of medications in causing dry eye. Journal Ophthalmology, 2012: 285851. DOI: 10.1155/2012/285851
Silva, P.S., Cavallerano, J.D., Sun, J.K., Soliman, A.Z., Aiello, L.M., Aiello, L.P. (2012) Nonmydriatic ultrawide field retinal imaging compared with dilated fundus examination for detection of diabetic retinopathy. American Journal of Ophthalmology, 154(3): 549-559. 10.1016/j.ajo.2012.03.019
Scanlon, P.H. (2017) The English National Screening Programme for diabetic retinopathy 2003-2016. Acta Diabetologica, 54(6): 515-525. 10.1007/s00592-017-0974-1
Abramoff, M.D., Lou, Y., Erginay, A., Clarida, W., Amelon, R., Folk, J.C., et al. (2016) Improved automated detection of diabetic retinopathy on a publicly available dataset through integration of deep learning. Investigative Ophthalmology & Visual Science, 57(13): 5200-5206. DOI: 10.1167/iovs.16-19964 DOI: of DOI: DOI:
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